2nd person cured of HIV thanks to stem cell transplant
In this second case, the person received a stem cell transplant with cells that did not express the CCR5 gene, which produces a protein that helps the virus enter cells.
The cells without the CCR5 gene were part of a bone marrow transplant, which the person was undergoing as a treatment for Hodgkin lymphoma.
Following the transplant, and at 30 months after the person ceased antiretroviral therapy, doctors confirmed that the HIV viral load remained undetectable in blood samples.
Chinese biophysicist He Jianku 贺建奎 was right when He made expansive claims of a medical breakthrough that could “control the HIV epidemic”.https://www.theguardian.com/…/china-gene-edited-baby…. He is in jail for a 3-years sentence because he was accused by the world to have violated ethics. Perhaps he should be un-villanized now, may be even win a Nobel Prize.Edit or delete this
“Turning the tide” — Xi leads anti-virus war toward victory
President Xi Jinping on Tuesday inspected the COVID19 outbreak epicenter in central China, pledging a continuous fight toward victory as prevention and control efforts have “turned the tide.”
The inspection to Wuhan, Hubei Province, took the president to a hospital treating severely ill COVID-19 patients and a residential community. He visited patients, medics, community residents and workers, police officers, military personnel, officials and volunteers who have been fighting the novel coronavirus.
Xi, also general secretary of the Communist Party of China (CPC) Central Committee and chairman of the Central Military Commission, called for firm, solid and meticulous prevention and control efforts to defend Hubei and Wuhan.
Xi said thanks to hard work, the situation in Hubei and Wuhan has shown positive changes with important progress, but the task of prevention and control remains arduous.
Xi stressed continuing to take epidemic prevention and control as a task of paramount importance.
Praising the people of Wuhan, Xi said the positive trend in epidemic control could not have been achieved without their sacrifice, devotion, perseverance and efforts.
With their concrete actions, the people of Wuhan have demonstrated the strength and spirit of China, as well as the Chinese people’s love for their family and nation, which enables them to stick together through thick and thin, he said.
On behalf of the CPC Central Committee, Xi sent condolences to people who died in the epidemic and people who sacrificed their lives fighting on the front line.
Wang Huning, a member of the Standing Committee of the Political Bureau of the CPC Central Committee and a member of the Secretariat of the CPC Central Committee, also attended the inspection.
In Huoshenshan Hospital, the first leg of his inspection, Xi lauded medical workers as “the most beautiful angels” and “messengers of light and hope.”
The frontline medical workers have taken on the most arduous missions, Xi said, calling them “the most admirable people in the new era” who deserve the highest commendations.
Xi talked with patients in the hospital through a video link, and expressed his wishes for their quick recovery.
“All prevention and control measures taken by the CPC Central Committee against the virus are to prevent more people from being infected and save more patients’ lives,” Xi said.
Meeting medic representatives in the hospital, Xi said the spread of the virus has been basically curbed in Hubei and Wuhan, and attributed the achievement to efforts of the whole Party, the whole country and the whole society.
“But you are the biggest heroes,” Xi told the medics.
Leaving Huoshenshan Hospital, Xi came to a residential community. People quarantined at home waved to Xi from their balconies and windows. Xi waved back and expressed his regards.
Xi stressed the importance of communities in epidemic prevention and control, requiring grassroots Party organizations and Party members to play their key roles in containing the virus spread in communities.
He emphasized closely relying on the people to win the people’s war against the epidemic.
After the field inspection, Xi chaired a teleconference and delivered an important speech.
Xi said since the outbreak, the CPC Central Committee has taken the most comprehensive, rigorous and thorough prevention and control measures to resolutely curb the spread of the virus in Wuhan and Hubei.
“Initial success has been achieved in stabilizing the situation and turning the tide,” he said.
Xi said medical treatment should be given the top priority to improve the recovery rate and reduce mortality to the greatest extent under the principle of scientific and targeted treatment.
Noting that the fight against the virus is at a critical moment, Xi stressed further preventing the spread and exportation of cases.
Xi demanded more understanding and tolerance for people in Hubei and Wuhan if some vent their feelings for long time under self-quarantine, as well as efforts to ensure the supply of their life necessities.
The epidemic will not affect the fundamentals of Hubei’s steady and long-term sound economic development, Xi said, urging implementation of policies and measures to support enterprises, stabilize employment and create more jobs.
Calling the response to the virus a “test” for China’s system and capacity for governance, which has brought both experience and lessons, Xi demanded efforts to fix the shortcomings and weak links as soon as possible.
Xi urged Party organizations, members and officials to shoulder responsibilities, adopt sound prevention and control measures and improve their capabilities in the test.
Xi visited Wuhan, is it over?
Great bustard elegantly showing off its bizarre features
The Lockdown – One month in Wuhan
Many think coronavirus is China’s ‘Chernobyl moment’, but the authoritarian regime could prove them wrong
Here’s a dangerous idea: what if it turns out that an authoritarian regime is better-equipped to handle the coronavirus emergency than liberal democracies?
What if the Chinese Communist Party teaches us all a lesson?
It isn’t supposed to be that way. Labelled secretive and paranoid by the West, China is meant to be panic-stricken about the mystery killer virus spiralling out of control and turning into an existential crisis.
It should be China’s Chernobyl moment: harkening back to the nuclear disaster in 1986, that is now widely accepted as the tipping point that helped usher in the end to the Soviet Union.
President Xi Jinping Had a Phone Call with US President Donald Trump
President Xi Jinping spoke with US President Donald Trump on the phone on the morning of 7 February.
President Xi highlighted the all-out efforts made by the Chinese government and people to fight the novel coronavirus outbreak. Featuring nationwide mobilization, across-the-board arrangements and rapid response, it is a people’s war against the epidemic with the most comprehensive and rigorous measures. Such efforts are producing results. China has full confidence and capability to prevail over the epidemic. The long-term upward trajectory of the Chinese economy remains unchanged.
Xi affirmed China’s commitment to protecting the lives and health of not only its own people but also other people around the world. With openness, transparency and a sense of responsibility, China has kept WHO, the United States and other countries and regions updated, and has invited WHO and other experts to conduct field visits in Wuhan. As the first line of defence against the epidemic, China has taken timely, decisive and forceful measures, which have been fully recognized and highly appreciated by WHO and many countries.
Xi noted the continuing communication over the epidemic between China and the US. He expressed appreciation for President Trump’s positive comments on China’s efforts on different occasions, and thanked the various communities in the US for their donations. It takes joint efforts from all countries to contain epidemics. The fight against the novel coronavirus outbreak has come to a crucial stage. WHO has repeatedly given its professional advice and called on all countries to avoid overreaction. China hopes that the US will evaluate the situation calmly and develop and adjust its response in line with the actual situation. China and the US should maintain communication and strengthen coordination to jointly control the epidemic.
President Trump expressed full support for China’s efforts to control the epidemic and readiness to send experts to China and provide other forms of assistance. The fact that China has finished building special hospitals for the patients in a matter of days is impressive. It fully demonstrates China’s exceptional ability of organization and response.
Trump expressed confidence that the Chinese people, under the leadership of President Xi, will win the battle against the outbreak. He said that the US has confidence in China’s economic growth. The US will be very calm in its response to the epidemic and continue communication and cooperation with China through bilateral and WHO channels.
The dwarf planet 2007 OR10 is officially Gonggong (龚工)! It’s the first major solar system body with a Chinese name. Its satellite is Xiangliu (相柳)
Gonggong has a reddish hue and might be able to sustain some sort of stinky, methane atmosphere.
Hopefully this celestial object doesn’t take on the characteristics of its namesake, who’s known for causing much suffering and destruction in the form of floods and even knocking the Earth’s axis off center. Perhaps if we’re lucky, the influence of Xiangliu will keep those tendencies in check.
An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance
- NLRP3 is modified by acetylation and deacetylated by SIRT2
- •NLRP3 acetylation facilitates the activation of the NLRP3 inflammasome
- •SIRT2 prevents and reverses aging-associated inflammation and insulin resistance
- •NLRP3 deacetylation regulates aging-associated inflammation and insulin resistancehttps://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30009-7?fbclid=IwAR2BglOkiD6-fvJiPctgl95_8Ytz4o5TI6N8Ftau5JrrQD_aDcxsUJCXEkc