- NLRP3 is modified by acetylation and deacetylated by SIRT2
- •NLRP3 acetylation facilitates the activation of the NLRP3 inflammasome
- •SIRT2 prevents and reverses aging-associated inflammation and insulin resistance
- •NLRP3 deacetylation regulates aging-associated inflammation and insulin resistancehttps://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30009-7?fbclid=IwAR2BglOkiD6-fvJiPctgl95_8Ytz4o5TI6N8Ftau5JrrQD_aDcxsUJCXEkc